Articles

Genomic malaria surveillance of antenatal care users detects reduced transmission following elimination interventions in Mozambique

Genomics reveals heterogeneous Plasmodium falciparum transmission and selection signals in Zambia

Safety and efficacy of malaria vaccine candidate R21/Matrix-M in African children: a multicentre, double-blind, randomised, phase 3 trial

 Promising Results for New Malaria Vaccine in African Children A phase 3 clinical trial published in The Lancet provides strong evidence that a new malaria vaccine, R21/Matrix-M, is highly efficacious and safe in African children. The randomized controlled trial was conducted at sites across four sub-Saharan African countries from 2021-2022. Nearly 5000 children aged 5-36 months received three doses of the R21/Matrix-M vaccine or a control rabies vaccine.

Bridging the gap to malaria vaccination in Africa: Challenges and opportunities

Cabo Verde eliminates malaria

Integrating vaccines and monoclonal antibodies into malaria prevention

World Malaria report 2023

Malaria in 2022: Increasing challenges, cautious optimism

Harnessing AI to Predict Malaria Outbreaks: A Game-Changer in Disease Prevention

The art of medicine Artesunate versus quinine: the controlled trials watershed

Project Report: The Sciback-skit programme: Engaging young people as malaria ambassadors in Kenya

In this project from the International Centre of Insect Physiology and Ecology in Kenya and funded by the DELTAS Africa CPE Seed Fund, high school students were educated about malaria and scientific research, to inspire them to become ambassadors in their communities, and to go on to have careers in science.

Epidemiology, Biodiversity, and Technological Trajectories in the Brazilian Amazon: From Malaria to COVID-19

The Amazon biome is under severe threat due to increasing deforestation rates and loss of biodiversity and ecosystem services while sustaining a high burden of neglected tropical diseases. Approximately two thirds of this biome are located within Brazilian territory. There, socio-economic and environmental landscape transformations are linked to the regional agrarian economy dynamics, which has developed into six techno-productive trajectories (TTs).

Cost-effectiveness of intermittent preventive treatment with dihydroartemisinin-piperaquine for malaria during pregnancy: an analysis using efficacy results from Uganda and Kenya, and pooled data

The authors aimed to estimate the cost-effectiveness of intermittent preventive treatment in pregnancy with dihydroartemisinin-piperaquine (IPTp-DP) versus IPTp-SP to prevent clinical malaria infection (and its sequelae) during pregnancy. Findings suggest that among HIV-negative pregnant women with high uptake of long-lasting insecticidal nets, IPTp-DP is cost-effective in areas with high malaria transmission and high sulfadoxine-pyrimethamine resistance. These data provide a comprehensive overview of the current evidence on the cost-effectiveness of IPTp-DP. Nevertheless, before a policy change is advocated, we recommend further research into the effectiveness and costs of different regimens of IPTp-DP in settings with different underlying sulfadoxine-pyrimethamine resistance.

Project Report: Bate Papo Vacina! (Let’s get vaccinated!)

This blog style project reflection from Village Reach gives an introduction to the different aspects of their research project exploring barriers to vaccination in Mozambique.

Locating Zika Social Change and Governance in an Age of Mosquito Pandemics

Melissa Kapulu: Malaria transmission and human infection studies [Interview@University of Oxford]

Literature: Why do people participate in mass antimalarial administration? Findings from a qualitative study in Nong District, Savannakhet Province, Lao PDR (Laos).

This article draws on qualitative data to explore the factors that led to high population coverage (>87%) of mass drug administration (MDA) as part of targeted malaria elimination (TME)* in the Greater Mekong sub-region of South East Asia. It looks at the community engagement and education activities (including health education through theatre, posters, village meetings, and house-to-house visits) were undertaken to promote the uptake of MDA in target communities.

Article: Community Engagement for the Rapid Elimination of Malaria: the Case of Kayin State, Myanmar

This article outlines Community Engagement efforts linked to a Targeted Malaria Elimination (TME) project in four Kayin State villages, in Myanmar where there is a real threat from the spread of drug resistant parasites. The Community Engagement programme was aimed at promoting population uptake and adherence to Mass drug administrations (MDA) in the region.