A recent correspondence in Nature Medicine outlines a crucial framework for enhancing the acceptance and distribution of newly approved malaria vaccines in Africa. With two new vaccines (RTS,S/AS01 and R21/Matrix-M) approved for use in children in malaria-endemic African countries, there's potential to prevent half a million child deaths annually. However, vaccine hesitancy, partly resulting from misinformation spread during the COVID-19 pandemic, poses a significant challenge. The authors propose a comprehensive community engagement strategy to address this hesitancy and boost vaccine uptake. The framework emphasizes tailored approaches for diverse African communities, involving local organizations, faith leaders, and influencers. It highlights the importance of socio-behavioral research and culturally sensitive communication. This article provides  insights for policymakers, health professionals, and community leaders involved in malaria prevention and vaccine implementation in Africa, offering a roadmap to overcome barriers and maximize the impact of these vaccines.

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Global Health  Malaria  

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